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343 | Tom Griffiths on The Laws of Thought
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AMA | Feb 2026
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Rachell Powell on Evolutionary Convergence, Morality, and Mind
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Stewart Brand on Maintenance as an Organizing Principle
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Rebecca Newberger Goldstein on What Matters and Why It Matters
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Ned Block on Whether Consciousness Requires Biology
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Holiday Message 2025 | The Romance of the University
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AMA | December 2025
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Ryan Patterson on the Physics of Neutrinos
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Kevin Zollman on Game Theory, Signals, and Meaning
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Anil Ananthaswamy on the Mathematics of Neural Nets and AI
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AMA | November 2025
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Andrew Jaffe on Models, Probability, and the Universe
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Daniel Whiteson on the Physics of and by Aliens
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Gordon Pennycook on Unthinkingness, Conspiracies, and What to Do About Them
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Dmitri Tymoczko on the Mathematics Behind Music
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AMA | October 2025
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Solo: Fine-Tuning, God, and the Multiverse
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Petter Törnberg on the Dynamics of (Mis)Information
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Steven Pinker on Rationality and Common Knowledge
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Mary Roach on Replacing Parts of Our Bodies
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AMA | September 2025
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Cass Sunstein on Liberalism
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Natalie Batalha on What We Know and Will Learn About Exoplanets
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Alvy Ray Smith on Pixar, Pixels, and the Great Digital Convergence
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Elizabeth Mynatt on Universities and the Importance of Basic Research
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AMA | August 2025
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Jacob Barandes on Indivisible Stochastic Quantum Mechanics
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Philip Pettit on Language, Agency, Politics, and Freedom
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David Tong on Open Questions in Quantum Field Theory
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AMA | July 2025
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Solo: Complexity and the Universe
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Bryan Van Norden on Philosophy From the Rest of the World
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Edward Miguel on the Developing Practice of Development Economics
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Nicole Rust on Why Neuroscience Hasn't Solved Brain Disorders
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AMA | June 2025
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Niayesh Afshordi and Phil Halper
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Branden Fitelson on the Logic and Use of Probability
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Karen Lloyd on the Deep Underground Biosphere
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Eric Topol on the Changing Face of Medicine and Aging
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AMA | May 2025
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Thomas Levenson on the Mutual History of Humans and Germs
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Annaka Harris on Whether Consciousness is Fundamental
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AMA | April 2025
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Marc Kamionkowski on Dark Energy and Cosmic Anomalies
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Christof Koch on Consciousness and Integrated Information
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Alison Gopnik on Children, AI, and Modes of Thinking
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AMA | March 2025
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Kevin Peterson on the Theory of Cocktails
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Helen Czerski on Our Energetic Oceans
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Lilliana Mason on Polarization and Political Psychology
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Bonus | Cuts to Science Funding and Why They Matter
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James Evans on Innovation, Consolidation, and the Science of Science
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AMA | February 2025
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James P. Allison on Fighting Cancer with the Immune System
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Chris Kempes on the Biophysics of Evolution
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Tina Eliassi-Rad on Al, Networks, and Epistemic Instability
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Solo: Does Time Exist?
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Holiday Message | Hits and Misses
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Michael Wong on Information, Function, and the Origin of Life
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Jeff Lichtman on the Wiring Diagram of the Brain
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AMA | December 2024
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Emily Wilson on Homer, Poetry, and Translation
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Brandon Ogbunu on Fitness Seascapes and the Course of Evolution
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Solo: Emergence and Layers of Reality
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AMA | November 2024
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Addy Pross on Dynamics, Stability, and Life
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Doyne Farmer on Chaos, Crashes, and Economic Complexity
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Jonathan Birch on Animal Sentience
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AMA | October 2024
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Venki Ramakrishnan on the Biology of Death and Aging
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Hahrie Han on Making Multicultural Democracy Work
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Cari Cesarotti on the Next Generation of Particle Experiments
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Max Richter on the Meaning of Classical Music Today
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AMA | September 2024
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Jean-Paul Faguet on Institutions and the Legacy of History
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Blaise Agüera y Arcas on the Emergence of Replication and Computation
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Nate Silver on Prediction, Risk, and Rationality
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AMA | August 2024
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Doris Tsao on How the Brain Turns Vision Into the World
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Daron Acemoglu on Technology, Inequality, and Power
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Joel David Hamkins on Puzzles of Reality and Infinity
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Ask Me Anything | July 2024
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Samir Okasha on the Philosophy of Agency and Evolution
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François Chollet on Deep Learning and the Meaning of Intelligence
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Ellen Langer on Mindfulness and the Body
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Kieran Healy on the Technology of Ranking People
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AMA | June 2024
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Cumrun Vafa on the Universe According to String Theory
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Gavin Schmidt on Measuring, Predicting, and Protecting Our Climate
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Solo: Quantum Fields, Particles, Forces, and Symmetries
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AMA | May 2024
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Gizem Gumuskaya on Building Robots from Human Cells
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Stefanos Geroulanos on the Invention of Prehistory
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Leslie Valiant on Learning and Educability in Computers and People
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AMA | April 2024
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Claudia de Rham on Modifying General Relativity
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Solo: The Coming Transition in How Humanity Lives
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Sahar Heydari Fard on Complexity, Justice, and Social Dynamics
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AMA | March 2024
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